If you are lucky enough to be staying in an apartment in Soho or Greenwich Village (as opposed to a hotel with no more kitchen than an electric kettle) - the Gourmet Garage (which has been there for yonks) is a great spot to pick up any fresh food or grocery item you need from breakfast through to dinner. Its not far from Dean and Delucca but a little bit cheaper with a slightly less glamourous vibe - more neighbourhood and earthy.
But still packed to the rafters with loads of excellent foodstuffs.
Apparently there are 6 outlets on Manhattan - so check out one near you.
